The world’s first benchtop PET/CT system
G8 PET/CT delivers high-resolution, high-sensitivity PET integrated with a sub-minute, low dose microCT. The G8 provides fully quantitative data, while maintaining workflow advantages including docking stations with imaging chambers, integrated anesthesia, and intuitive imaging protocol creation software. Highly versatile, the G8 is designed to rapidly integrate into your current preclinical research workflow in a broad-range of applications including neurology, oncology, cardiology, biodistribution, and drug discovery.
Applications
Neurology
[18F]Fallypride allows for non-invasive in vivo imaging of dopamine D2/3 receptors, in mice and rats providing invaluable mechanistic insights into neurodegenerative diseases.
Oncology
[18F]FDG-PET is a robust and reliable probe for investigating the glycolytic potential of tumors. FDG- PET-CT allows for rapid detection of changes in tumor glucose metabolism, an early indicator of treatment efficacy. This in vivo assay is an integral tool in the drug discovery researchers toolkit.
Bone Metabolism
When administered in vivo, NaF incorporates rapidly into the apatite crystals of bones. Regions of bone metabolism can be quickly identified. PET readouts have applications in various skeletal disorders such as osteoporosis and tumor osteolysis, often a hallmark of metastatic disease.
Immunology
Antibody imaging (with 89Zr, 124I, 64Cu) is a sensitive, non-invasive means for molecular characterization to guide diagnosis, therapy selection, and monitoring treatment in cancer.
Software
Introducing the G8 PET/CT Acquisition Engine
Quickly generate complex protocols with just a few clicks, or use preset protocols provided with the software. Export data in DICOM format for analysis and seamless fusion to downstream platforms. By offering multiple modes of operation, you get ultimate system flexibility.
General
Relies on preloaded protocols and optimized imaging parameters for a simple, convenient acquisition workflow for users of all experience levels.
Physicist
Emphasizes operational flexibility and gives experienced PET users the ability to modulate key acquisition and reconstruction parameters across all user profiles.
Administrator
Allows for easy exporting of usage data by project or users for grant or billing reconciliation.
Image Analysis
All PET data is collected in list mode format and images are stored in DICOM format, allowing for exportation and analysis is a variety of software platforms, including Living Image© and VivoQuant™.
Live Link To Animal
You spend a lot of time validating and preparing your animal model – why leave its well-being to chance?
The built-in video camera allows you to monitor the physiological condition of your mice and rats in real time, taking the guesswork out of anesthesia management for an optimal, safe, and stable imaging environment.
Hardware Specifications
Engineering Specifications
Unit width: 56 cm (22”)
Unit depth: 66 cm (26”)
Unit height: 71 cm (28”)
Unit weight: 90 kg (200 lbs)
Operating room temperature: 65 – 75 °F (18 – 24 °C)
Operating humidity: 30 – 70% non-condensing
Power requirements: 4 A @ 110 V (2 A @ 220 V)
PET Specifications
Axial FOV: 9.5 cm
Transaxial FOV: 4.7 cm
Detector element size: 1.8 mm x 1.8 mm x 7 mm
Peak absolute system sensitivity*: >14%
Reconstructed resolution at center of FOV*: 1.4 mm
Average energy resolution: 18%
Energy window range: 150 – 650 keV
Total number of detector elements: 5,408 Reconstruction algorithm: 3D ML-EM
CT Specifications
X-ray Source: 50 kVp, 200uA
X-ray Camera: 75 micron pixels, 14bits, CMOS+CsI flat panel
Camera Speed: 24 fps
Field of View: 100mm axial by 50mm transaxial
Standard Scan Time: <60 seconds